One of the most challenging tasks in clinical trials is finding the maximum tolerated dose (MTD) to be tested in the next phase.An assurance for the safety of the patients and recommendation of a suitable dose for phase II are the main objectives of a phase I trial.The MTD can be identified through various approaches.A non-parametric approach, know
A reinforcement neural network-based grid-integrated photovoltaic GAGS (PV) system with a battery management system (BMS) was developed to enhance the efficiency and reliability of renewable energy systems.In such a setup, the PV system generates electricity, which can be used immediately, stored in batteries, or fed into the grid.The challenge lie
Background and aim Strictures are a major complication of esophageal endoscopic submucosal dissection (ESD) for superficial esophageal carcinoma.Post ESD, stricture develops during the process of scar formation, which is related to inflammation caused by ESD.We planned a study to evaluate whether certain electrosurgical unit modes could attenuate s
Seagrass meadows provide important ecosystem services including carbon sequestration, coastal protection from erosion, and sustained biodiversity and fisheries thereby improving the wellbeing and livelihoods of coastal communities.The erosion of millenary deposits of intertwined roots and rhizomes of Posidonia results in the formation of three-dime
Digital image analysis (DIA) is a new method in assessment of islet amount, which is expected to provide reliable and consistent results.We compared this method with conventional counting of small numbers of rat islets.Islets were isolated from 8 pancreases and counted in 24 samples in duplicate, first routinely fast key wire by sizing according to